منابع مشابه
The prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
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The kidney kallikrein-kinin system plays important roles in inflammation, coagulation, angiogenesis, and regulation of vessel tone and permeability. In this issue of the JCI, Liu et al. provide data that suggest a protective role for kallikrein in animal models of anti-glomerular basement membrane(GBM) antibody-induced nephritis, an experimental model of Goodpasture disease (see the related art...
متن کاملCirculating DNA in Systemic Lupus Erythematosus
Immunoprecipitable double-stranded (dsDNA) was previously shown to persist in the circulation ofa clinically recognizable subgroup of patients with systemic lupus erythematosus (SLE). Plasma from 10 such patients was subjected to a DNA isolation procedure that used a combination ofproteolysis, phenol extraction, and hydroxylapatite adsorption and elution in the presence of urea. The isolated ds...
متن کاملHidden face of lupus nephritis exposed: Isolated tubulointerstitial lupus nephritis.
Implication for health policy/practice/research/medical education: Systemic lupus erythematosus (SLE) is a common multisystemic immunological disorder with protean manifestations. It commonly involves the kidney, which is associated with significant morbidity and mortality. In the kidney, it typically affects glomeruli and blood vessels with secondary involvement of tubulointer-stitial componen...
متن کاملLupus nephritis and lupus band test.
Twenty-seven patients with histologically confirmed lupus nephritis were studied to identify the incidence of lupus band and its significance to histological patterns of nephritis and complement levels. It was found that the kidney involvement is 2.5 times more frequent in lupus band positive patients. The association of a positive lupus and low C3 level signifies the presence of diffuse prolif...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1988
ISSN: 0085-2538
DOI: 10.1038/ki.1988.25